Sir 10:10 There is not a more wicked thing than to love money: for such a one setteth even his own soul to sale: because while he liveth he hath cast away his bowels.
Sir 10:11 All power is of short life. A long sickness is troublesome to the physician.
Sir 10:12 The physician cutteth off a short sickness: so also a king is to day, and to morrow he shall die.
Sir 10:13 For when a man shall die, he shall inherit serpents, and beasts, and worms.
Sir 10:14 The beginning of the pride of man, is to fall off from God:
Sir 10:15 Because his heart is departed from him that made him: for pride is the beginning of all sin: he that holdeth it, shall be filled with maledictions, and it shall ruin him in the end.
Sir 10:16 Therefore hath the Lord disgraced the assemblies of the wicked, and hath utterly destroyed them.
Sir 10:17 God hath overturned the thrones of proud princes, and hath set up the meek in their stead.
Sir 10:18 God hath made the roots of proud nations to wither, and hath planted the humble of these nations.
Sir 10:19 The Lord hath overthrown the lands of the Gentiles, and hath destroyed them even to the foundation.
Sir 10:20 He hath made some of them to wither away, and hath destroyed them, and hath made the memory of them to cease from the earth.
Sir 10:21 God hath abolished the memory of the proud, and hath preserved the memory of them that are humble in mind.
Verse 15 identifies pride as the source of sin. Pride can feed and cause so many other sins and it is the beginning of our departure from God. Believing we don't need Him is the first step in ridding Him from our minds and our lives.
This isn't the only place this is stated, but notice in verse 20 God can make the wicked disappear entirely so even the memory of them is no longer present. It is well within God's power to make such a city disappear entirely.